This answer depends on if you count the playoffs. Counting them, the most points we've scored is the 62-7 drubbing of the Dolphins in Marino's last game. '99 playoffs. This would make our 49-11 victory over Oakland in 2007 second.
If you do not count playoffs, then the Oakland game is first, with a 48-0 shutout in 2000 against the Browns second.